ODCs

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2 OMIM references -
1 associated gene
10 signs/symptoms

PROTEIN INTERACTIONS: 1

3 OMIM references -
5 associated genes
No signs/symptoms info

Fibronectin glomerulopathy

Autoimmune lymphoproliferative syndrome


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	FN1	(0.76)	FASLG

Citations in the biomedical literature:

Fibronectin glomerulopathy		Autoimmune lymphoproliferative syndrome
	Synonym(s): - GFND - Glomerulopathy with fibronectin deposits		Synonym(s): - ALPS - Canale-Smith syndrome - FAS deficiency

	Classification (Orphanet): - Rare genetic disease - Rare renal disease		Classification (Orphanet): - Rare genetic disease - Rare hematologic disease - Rare immune disease - Rare oncologic disease

	Classification (ICD10): - Diseases of the genitourinary system -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant

	External references: 2 OMIM references - No MeSH references		External references: 3 OMIM references - 1 MeSH reference: D056735

Fibronectin glomerulopathy
	Very frequent - Autosomal dominant inheritance - Chronic arterial hypertension - Edema of the legs / lower limbs - Functional anomalies of the kidney and the urinary tract - Hematuria / microhematuria - Nephrotic syndrome - Proteinuria - Renal failure - Renal glomerular defect / glomerulopathy Occasional - Intracranial / cerebral / meningeal hemorrhage
Autoimmune lymphoproliferative syndrome
(no data available)